SAMe

Pronounced "sammy", SAMe is a chemical that is sold as a dietary supplement (and, in Europe, as a prescription medication) and has been studied extensively as a possible treatment for osteoarthritis and depression. Short for S-adenosyl methionine, SAMe is produced naturally, and small amounts are found in virtually every part of the body.

 

SAMe 는 면역계에서 역할을 하며 세로토닌, 멜라토닌, 도파민과 같은 기분을 조절하는 뇌화학물질을 생성하거나 부숴버리는 것을 도와준다. 이것은 또한 연골생성이나 뼈와 결합된 단단한 조직, 관절의 막들을 만드는데 관여하며, 인체의 골격 유지에 도움을 준다.

 

However, the body produces less SAMe as it ages, and scientists believe that taking a supplement of the chemical may help fight the symptoms of certain conditions and disease. It may help alleviate a pain from osteoarthritis. Preliminary research also suggests that SAMe also has potential for treating mild to moderate depression and seems to begin working more quickly and just as effectively as antidepressant medications without the side effects frequently asociated with these drugs, such as headaches, sleeplessness, and sexual dysfunction. It is not clear how SAMe relieves depression, so doctors advise against taking it at the same time as antidepressants. More research about its safety and effectiveness, especially over long periods of time, is needed.

 

SAMe 는 가장 광범위하게 캡슐형태로써 사용가능하며, 비록 주사요법 또한 임상에서 연구되어 지고 있다. 하루에 1600 밀리그램, 최대 6주간 까지의 복용이 안전하다. 부작용으로는 오심, 피부발진, 구건 혹은 귀의 뜨거운 감각이나 가려움증 등이 포함된다. 이 보충제는 혈당 수치를 내려주기도 해서 당뇨나 저혈당증을 갖고 있는 환자들은 SAMe 를 신중히 사용해야 한다.

 

 

 

Early studies suggest that SAMe may also be helpful in treating attention-deficit/hyperactivity disorder, fibromyalgia, and cholestasis ― a buildup of bile in the liver.

 

SAMe also occurs in plants and other animals.

 

Although SAMe is often marketed as a "natural" cure for depression and arthritis, it is in fact a synthetic version of a chemical made in the body. Some experts believe that this makes it a drug, not a supplement, and that it should be regulated as a drug.